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Laboratory Safety
National Summary

This topic covers OSHA’s requirements for laboratory safety.

Because laboratories differ from industrial operations, particularly in their use and handling of hazardous chemicals, OSHA has a different set of requirements for laboratories than other facilities. The most important piece of OSHA’s Occupational Exposure to Chemicals in Laboratories standard is a requirement for laboratories to produce a chemical hygiene plan that establishes standard operating procedures for handling hazardous chemicals.

Components of a chemical hygiene plan include procedures for reducing employee exposure to hazardous chemicals (e.g., engineering controls, ventilation, and use of PPE), employee training, emergency measures, provisions for medical consultation and examination of workers, requirements for approval of new lab activities, and special precautions for working with particularly hazardous substances.

Click here for a chemical hygiene plan that you can customize for your facility.

For related resources and training materials, refer to the following topics:

Applies to News & White Papers
Directives 11/18/1991 - CPL 2.35 CH-19 - Changes to the Regulatory and General Industry Standard Alleged Violation... 07/22/2003National
Regulations 29 CFR § 1910.1450 Occupational exposure to hazardous chemicals in laboratories  National
Final Rules 29 CFR 1910 - Occupational Exposure to Hazardous Chemicals in Laboratories 01/21/2013National
Interpretations Applicability of the OSHA Laboratory Standard to laboratories within the electric utility industry [1910.1200; 1910.1450] 01/09/1991National
Questions & Answers Are hazardous chemicals such as acids and bases allowed to be stored in glass bottles with either a glass or cork stopper? My concern is if bottle is knocked over then a spill will occur. 10/16/2017National
Questions & Answers Can you please tell me if we need to install an oxygen sensor in a cleanroom space that we are currently using dewars of nitrogen in? The two labs are 70 feet by 40 feet and 78 feet by 38 feet and they are connected by an opening between the two rooms... 08/22/2013National
Training Activities Chemical Hygiene Safety Activity (Word)  National
Interpretations Chemical manipulation, production, multiple uses of chemicals in QC labs [1910.1200; 1910.1450] 01/17/1991National
Questions & Answers Do laboratory fume hoods need to be inspected annually or have any monitoring tests performed on them? 03/06/2015National
Questions & Answers Is it ok to place a fume hood that is 78"x29" in a small room 113"x131"? This room has a front and back door that leads to another room. 01/04/2016National
Questions & Answers Is there any requirement that a sink faucet needs to be in a lab that contains corrosive chemicals? The lab already has an eye wash and safety shower. 03/25/2019National
Checklists Lab Safety Best Practices Checklist  National
Interpretations Labeling requirements under the HAZCOM and Laboratory standards; use of safe needle devices [1910.1200(f); 1910.1450(h)(1)(i); 1910.1030(d)(2)(i)] 01/11/2001National
Checklists Laboratory Chemical Safety Regulatory Compliance Audit Checklist  National
7 Minute Safety Trainer Laboratory Safety (Outline)  National
Handouts Laboratory Safety (Word)  National
Quizzes Laboratory Safety [7-Minute Safety Trainer]  National
Handouts Laboratory Safety [7-Minute Safety Trainer]  National
Quizzes Laboratory Safety [7-Minute Safety Trainer] - Spanish  National
Handouts Laboratory Safety [7-Minute Safety Trainer] - Spanish  National
Training Activities Laboratory Safety Activity (Word)  National
Guidance Documents Laboratory Safety Guidance (OSHA document)  National
Toolbox Talks Laboratory safety: Handling arboviruses safely  National
Interpretations Laboratory Standard does not cover routine tests supporting production but non-routine, non-production-related tests are covered 08/08/1990National
Interpretations Laboratory Standard's application in testing building products [1910.1200; 1910.1450] 01/16/1991National
Questions & Answers My client has a question regarding the requirement to have a Chemical Hygiene Plan (CHP) in QC labs and in Research and Development Labs:Is there any exemption… does OSHA accept having different SOPs that covers the requirements, such as haz. Co 12/06/2016National
Questions & Answers What are the requirements (If any - certification) to be a Chemical Hygiene Officer? And what are the responsibilities of the CHO? 04/11/2014National
Interpretations Whether employers may designate an outside consultant as the Chemical Hygiene Officer under 1910.1450. 02/15/2008National
Questions & Answers Who is the regulating authority for annual fume hood inspections? 10/27/2009National
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